Order confirmation email is not sent(magento2.1)

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I want to send the email just when new order from customer.

But Email the order is not sent by email anymore. The "Order" and "Order Comments" setting in the System->Configuration->Sale Emails are Enabled.

Website run on VPS( Apache2+PHP ver7.0.8+MySQL 5+Ubuntu 16 +MAGENTO 2.1)

Where can I do? Please help me. Thank very much