How Do People Handle Selling in Colorado Since the June Tax Law Changes

[nodiseos]

Colorado in its infinite wisdom has home rule for sales tax, meaning that since June,  if any vendor shops products to a city, county or town in Colorado, it is required to calculate, collect and pay the sales taxes for that jurisdiction.  The state handles it for a bunch but to continue selling to everyone in CO, we'd have to file 71 different tax returns.  

How have people handled this?  I think the only realistic route for a small business like us is to disallow sales with delivery addresses in those 71 jurisdictions.  But I am unsure how to implement it on that level.  

Any lessons learned or advice most welcome.

[nodiseos]

How have people handled this?  I think the only realistic route for a small business like us is to disallow sales with delivery addresses in those 71 jurisdictions.  But I am unsure how to implement it on that level.  

Any lessons learned or advice most welcome.