Colorado in its infinite wisdom has home rule for sales tax, meaning that since June, if any vendor shops products to a city, county or town in Colorado, it is required to calculate, collect and pay the sales taxes for that jurisdiction. The state handles it for a bunch but to continue selling to everyone in CO, we'd have to file 71 different tax returns.
How have people handled this? I think the only realistic route for a small business like us is to disallow sales with delivery addresses in those 71 jurisdictions. But I am unsure how to implement it on that level.